Boston.com said the crash happened at around 7 a.m. and there was significant damage to the house, which is over 110 years old.
The news website said there were no injuries and crews had cleared the scene by around 8 p.m.
The crash happened in the middle of a morning snow storm that brought an inch or two of wet, slippery snow to the area.
It's by no means the first time a vehicle has crashed into a building in Somerville.
Here are some other accounts of vehicles smashing into homes and restaurants:
SUV Smashes into Union Square's Journeyman Restaurant
VIDEO: Car Crashes into Willoughby Street House
Pickup Truck Smashes into Taco Loco